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B6db families: 4.1.1.19.2

4.1.1.19 2
Activity 4.1.1.19
Description Arginine decarboxylase. (family 2)
Notes The family was built based on the sequence of the Escherichia coli (biodegradative) arginine decarboxylase, which is the only functionally validated enzyme.
The family encompasses only bacterial sequences belonging to the fold-type I group. (In contrast, plant arginine decarboxylases and the biosynthetic E. coli enzyme - included in family 4.1.1.19_1 - belong to the fold-type III group).

Note that the sequences from gram- bacteria (including E. coli) are longer than those from gram+ bacteria, mainly due to the presence of an additional N-terminal domain in gram- proteins.

PDB 2VYC;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
10
Sequences in seed alignment
BacteriaNP_243506 (Bacillus halodurans); ZP_00182964 (Exiguobacterium sp.); NP_622677 (Thermoanaerobacter tengcongensis); NP_250509.1 (Pseudomonas aeruginosa); NP_404807.1 (Yersinia pestis); NP_435607.1 (Sinorhizobium meliloti); ZP_00060969 (Clostridium thermocellum); ZP_00171293 (Ralstonia eutropha); SPEA_BACSU (Bacillus subtilis); ADIA_ECOLI (Escherichia coli);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence ADIA_ECOLI
Domain interval 140-607
Catalytic site 386 K
 
References Articles on 4.1.1.19.2
last changed 2009/06/30 14:26

B6db families