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B6db families: 4.1.1.25.a

4.1.1.25 a
Activity 4.1.1.25
Description Tyrosine decarboxylase (family a)
Notes This family has been constructed around three validated bacterial sequences, but it also includes a closely homologous archaeal sequence.
Fungal Phe decarboxylases (Family 4.1.1.53) are very similar in sequence (apart from an additional C-terminus domain) and retain a substantial activity towards tyrosine.
Plant enzymes with tyrosine decarboxylase activity have been included into EC 4.1.1.28 (Aromatic amino acid decarboxylase).
PDB 5HSI;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Reference sequence AAM46082
Domain interval 57-513
Catalytic site 392 K
 
References Articles on 4.1.1.25.a
last changed 2018/12/19 09:48

B6db families