B6db families : 4_1_1

	Activities \| Families \| Sequences \| Fold types \| References \| Help

4.1.1.96

Activity

4.1.1.96

Description

Carboxynorspermidine decarboxylase

Notes

Family composed of bacterial fold-type III enzymes, distantly related to Diaminopimelate decarboxylase (EC 4.1.1.20).

PDB

3N29;

PLP Fold Type

III

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type III

Number of sequences

Sequences in seed alignment

Bacteria

BAA06561 (Vibrio alginolyticus); ZP_02925472 (Verrucomicrobium spinosum DSM 4136); WP_002855819 (Campylobacter jejuni); YP_943630 (Psychromonas ingrahamii); WP_011372810 (Sulfurimonas denitrificans); YP_002263506 (Aliivibrio salmonicida LFI1238); EAU47139 (Roseovarius sp. HTCC2601); Q8D8D2 (Vibrio vulnificus); WP_014770421 (Sulfurospirillum barnesii); WP_046860196 (Sedimenticola thiotaurini); WP_092911974 (Hydrogenimonas thermophila); NP_245308 (Pasteurella multocida); EBA01096 (Marinobacter sp. ELB17); NP_231262 (Vibrio cholerae); NP_697368 (Brucella suis); EDM64791 (Moritella sp. PE36);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

BAA06561

Domain interval

14-244

Catalytic site

41 K

References

Deng X, Lee J, Michael AJ, Tomchick DR, Goldsmith EJ, Phillips MA. (2010) Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. J Biol Chem. 285 25708-19.

Lee J, Sperandio V, Frantz DE, Longgood J, Camilli A, Phillips MA, Michael AJ. (2009) An alternative polyamine biosynthetic pathway is widespread in bacteria and essential for biofilm formation in Vibrio cholerae J Biol Chem 284 9899-907.

Yamamoto S, Sugahara T, Tougou K, Shinoda S. (1994) Cloning and nucleotide sequence of the carboxynorspermidine decarboxylase gene from Vibrio alginolyticus Microbiology 140 3117-24.

Articles on 4.1.1.96

last changed

2018/05/08 08:54