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B6db families: 4.1.3.38.c

4.1.3.38 c
Activity 4.1.3.38
Description 4-amino-4-deoxychorismate lyase (family c)
Notes Family consttituted solely of fungal enzymes, and founded on the S. cerevisiae Abz2p. These sequences show only a very distant similarity to bacterial and plant 4-amino-4-deoxychorismate lyases.
PDB 4K6N;
PLP Fold Type IV
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type IV

Number of sequences
5
Sequences in seed alignment
FungiXP_451419 (Kluyveromyces lactis); NP_014016 (Saccharomyces cerevisiae); NP_986996 (Ashbya gossypii); XP_449930 (Candida glabrata); XP_001643896 (Vanderwaltozyma polyspora);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence NP_014016
Domain interval 117-360
Catalytic site 251 K
 
References
 Dai YN1, Chi CB, Zhou K, Cheng W, Jiang YL, Ren YM, Ruan K, Chen Y, Zhou CZ. (2013) Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase J Biol Chem 288 22985-92.

 Botet J, Mateos L, Revuelta JL, Santos MA. (2007) A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase Eukaryot Cell 6 2102-11.

Articles on 4.1.3.38.c
last changed 2014/02/25 10:45

B6db families