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4.1.3.38 c |
Activity |
4.1.3.38 |
Description |
4-amino-4-deoxychorismate lyase (family c) |
Notes |
Family consttituted solely of fungal enzymes, and founded on the S. cerevisiae Abz2p. These sequences show only a very distant similarity to bacterial and plant 4-amino-4-deoxychorismate lyases. |
PDB |
4K6N; |
PLP Fold Type |
IV |
PLP-dependent Domain |
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Number of sequences |
6 |
Sequences in seed alignment |
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Reference sequence |
NP_014016 |
Domain interval |
117-360 |
Catalytic site |
251 K |
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References |
Dai YN1, Chi CB, Zhou K, Cheng W, Jiang YL, Ren YM, Ruan K, Chen Y, Zhou CZ. (2013) Structure and catalytic mechanism of yeast 4-amino-4-deoxychorismate lyase J Biol Chem 288 22985-92. Botet J, Mateos L, Revuelta JL, Santos MA. (2007) A chemogenomic screening of sulfanilamide-hypersensitive Saccharomyces cerevisiae mutants uncovers ABZ2, the gene encoding a fungal aminodeoxychorismate lyase Eukaryot Cell 6 2102-11. Articles on 4.1.3.38.c |
last changed |
2014/02/25 10:45 |
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