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B6db families: 4.4.1.14

4.4.1.14
Activity 4.4.1.14
Description 1-aminocyclopropane-1-carboxylate synthase.
Notes A family constituted solely of plant enzymes and of a small subset of fungal sequences, similar to the functionally validated enzyme from P. citrinum (the actual physiological role of ACC synthase in fungi is not known).
PDB 1IAY;1IAX;1B8G;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
19
Sequences in seed alignment
FungiEAA64669 (Aspergillus nidulans ); JC7730 (Penicillium citrinum); EAA73897 (Gibberella zeae);
ViridiplantaeCAA81749 (Solanum tuberosum); 1A11_ORYSA (Oryza sativa); 1A12_ARATH (Arabidopsis thaliana); AAP14020 (Lactuca sativa); 1A11_CUCPE (Cucurbita pepo); CAB60831 (Citrus sinensis); 1A1C_SOYBN (Glycine max); AAR12136 (Pyrus communis); 1A14_LYCES (Lycopersicon esculentum); S26214 (Vigna radiata); AAQ88100 (Rosa hybrid cultivar); 1A12_LYCES (Lycopersicon esculentum); 1A1C_TOBAC (Nicotiana tabacum); AAN72122 (Arabidopsis thaliana); 1A12_CUCMA (Cucurbita maxima); 1A1C_MALDO (Malus domestica);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence 1A1C_MALDO
Domain interval 40-425
Catalytic site 273 K
 
References
 Wang D, Fan J, Ranu RS. (2004) Cloning and expression of 1-aminocyclopropane-1-carboxylate synthase cDNA from rosa (Rosa x hybrida) Plant Cell Rep 22 422-9.

 Kakuta, Y.; Igarashi, T.; Murakami, T.; Ito, H.; Matsui, H.; Honma, M. (2001) 1-Aminocyclopropane-1-carboxylate synthase of Penicillium citrinum: primary structure and expression in Escherichia coli and Saccharomyces cerevisiae Biosci Biotechnol Biochem 65 1511-8.

 Capitani G.; Hohenester, E.; Feng, L.; Storici, P.; Kirsch, J.F.; Jansonius, J.N. (1999) Structure of 1-aminocyclopropane-1-carboxylate synthase, a key enzyme in the biosynthesis of the plant hormone ethylene J Mol Biol 294 745-56.

 Sato, T.; Oeller, P. W.; Keller, J. A.; Theologis, A. (1991) The 1-aminocyclopropane-1-carboxylate synthase of Cucurbita. Purification, properties, expression in Escherichia coli, and primary structure determination by DNA sequence analysis J Biol Chem 266 3752-9.

 Van der Straeten, D.; Van Wiemeersch, L.; Goodman, H. M.; Van Montagu, M. (1990) Cloning and sequence of two different cDNAs encoding 1-aminocyclopropane-1-carboxylate synthase in tomato Proc Natl Acad Sci U S A 87 4859-63.

Articles on 4.4.1.14
last changed 2008/04/25 17:55

B6db families