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B6db families: 4.4.1.28.b

4.4.1.28 b
Activity 4.4.1.28
Description L-cysteine desulfidase (family b)
Notes This subfamily encompasses fold-type II enzymes for which a L-cys desulfhydrase activity has been reported.
Bacterial and plant enzymes probably evolved independently, even though both are clearly derived from cysteine synthases (2.1.5.47).
PLP Fold Type II
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type II

Number of sequences 7
Sequences in seed alignment
BacteriaNP_811992 (Bacteroides thetaiotaomicron); ZP_04970292 (Fusobacterium nucleatum); ZP_04568783 (Fusobacterium mortiferum);
ViridiplantaeNP_198155 (Arabidopsis thaliana); AFS17242 (Brassica napus); XP_002872303 (Arabidopsis lyrata); CAA71799 (Brassica juncea);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence ZP_04970292
Domain interval 6-294
Catalytic site 42 K
 
References
 Xie Y, Lai D, Mao Y, Zhang W, Shen W, Guan R. (2013) Molecular cloning, characterization, and expression analysis of a novel gene encoding L-cysteine desulfhydrase from Brassica napus. Mol Biotechnol. 54 737-46.

 Alvarez C, Calo L, Romero LC, García I, Gotor C. (2010) An O-acetylserine(thiol)lyase homolog with L-cysteine desulfhydrase activity regulates cysteine homeostasis in Arabidopsis Plant Physiol 152 656-69.

 Fukamachi, H.; Nakano, Y.; Yoshimura, M.; Koga, T. (2002) Cloning and characterization of the L-cysteine desulfhydrase gene of Fusobacterium nucleatum FEMS Microbiol Lett 215 75-80.

Articles on 4.4.1.28.b
last changed 2017/09/11 15:25

B6db families