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B6db families: 4.4.1.8.a

4.4.1.8 a
Activity 4.4.1.8
Description Cystathionine beta-lyase. (family a)
Notes Bacterial family, strictly related to cystathionine gamma-lyase (EC 4.4.1.1) and methionine gamma-lyase (4.4.1.11).
PDB 1CL1;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
18
Sequences in seed alignment
BacteriaAAK02878.1 (Pasteurella multocida); METC_SALTY (Salmonella typhimurium); AAL42579.1 (Agrobacterium tumefaciens str. C58 (U. Washington)); CAD15341.1 (Ralstonia solanacearum); METC_BORAV (Bordetella avium); ZP_00053889 (Magnetospirillum magnetotacticum); METC_HAEIN (Haemophilus influenzae); AAK23405.1 (Caulobacter crescentus CB15); ZP_00015109 (Rhodospirillum rubrum); AAF94821.1 (Vibrio cholerae); AAN55233 (Shewanella oneidensis); ZP_00034365 (Burkholderia fungorum); METC_ECOLI (Escherichia coli); ZP_00125269 (Pseudomonas syringae ); CAC46058.1 (Sinorhizobium meliloti); CAC89534.1 (Yersinia pestis); NP_697753 (Brucella suis ); ZP_00012095 (Rhodopseudomonas palustris);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence METC_ECOLI
Domain interval 7-392
Catalytic site 210 K
 
References
 Laber, B.; Clausen, T.; Huber, R.; Messerschmidt, A.; Egner, U.; Muller-Fahrnow, A.; Pohlenz, H. D. (1996) Cloning, purification, and crystallization of Escherichia coli cystathionine beta-lyase FEBS Lett 379 94-6.

 Gentry-Weeks, C. R.; Keith, J. M.; Thompson, J. (1993) Toxicity of Bordetella avium beta-cystathionase toward MC3T3-E1 osteogenic cells J Biol Chem 268 7298-314.

 Park, Y. M.; Stauffer, G. V. (1987) Cloning and characterization of the metC gene from Salmonella typhimurium LT2 Gene 60 291-7.

Articles on 4.4.1.8.a
last changed 2008/04/10 12:02

B6db families