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B6db families: 4.4.1.8.c

4.4.1.8 c
Activity 4.4.1.8
Description Cystathionine beta-lyase. (family c)
Notes A family composed by eukaryotic sequences (from planta and fungi) closely related to cystathionine gamma-lyases (family 4.4.1.1).
PDB 1IBJ;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
12
Sequences in seed alignment
FungiEAL00658 (Candida albicans ); AF401237 (Neurospora crassa); AF211176 (Botryotinia fuckeliana); AAB03241 (Emericella nidulans); EAA56719 (Magnaporthe grisea); EAA68828 (Gibberella zeae); ABM92783 (Hansenula polymorpha);
ViridiplantaeMETC_ARATH (Arabidopsis thaliana); BAA95820 (Oryza sativa ); CAL55420 (Ostreococcus tauri); AF082890 (Solanum tuberosum); XP_001764951 (Physcomitrella patens);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence METC_ARATH
Domain interval 88-460
Catalytic site 278 K
 
References
 Gidijala L, van der Klei IJ, Veenhuis M, Kiel JA. (2007) Reprogramming Hansenula polymorpha for penicillin production: expression of the Penicillium chrysogenum pcl gene FEMS Yeast Res 7 1160-7.

 Breitinger, U.; Clausen, T.; Ehlert, S.; Huber, R.; Laber, B.; Schmidt, F.; Pohl, E.; Messerschmidt, A. (2001) The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity Plant Physiol 126 631-42.

 Sienko, M.; Paszewski, A. (1999) The metG gene of Aspergillus nidulans encoding cystathionine beta-lyase: cloning and analysis Curr Genet 35 638-46.

 Ravanel, S.; Job, D.; Douce, R. (1996) Purification and properties of cystathionine beta-lyase from Arabidopsis thaliana overexpressed in Escherichia coli Biochem J 320 383-92.

Articles on 4.4.1.8.c
last changed 2008/04/14 19:33

B6db families