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B6db families: 5.1.1.1.b

5.1.1.1 b
Activity 5.1.1.1
Description Alanine racemase. (family b)
Notes A family constituted by just two fungal enzymes, completely different from their bacterial counterparts and from the S. pombe sequences.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
4
Sequences in seed alignment
FungiEER26822 (Coccidioides posadasii C735 delta SOWgp); CAA02484 (Tolypocladium inflatum); AAD47837 (Cochliobolus carbonum); EEP77449 (Uncinocarpus reesii);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence CAA02484
Domain interval 25-317
Catalytic site 220 K
 
References
 di Salvo ML1, Florio R, Paiardini A, Vivoli M, D'Aguanno S, Contestabile R. (2013) Alanine racemase from Tolypocladium inflatum: A key PLP-dependent enzyme in cyclosporin biosynthesis and a model of catalytic promiscuity Arch Biochem Biophys 529 55-65.

 Liu JL, Liu XQ, Shi YW. (2012) Expression, purification, and characterization of alanine racemase from Pseudomonas putida YZ-26. World J Microbiol Biotechnol. 28 267-74.

 Cheng, Y.Q. Walton, J.D. (2000) A eukaryotic alanine racemase gene involved in cyclic peptide biosynthesis J Biol Chem. 275 4906-4911.

Articles on 5.1.1.1.b
last changed 2014/07/10 20:49

B6db families