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5.1.1.21 |
Activity |
5.1.1.21 |
Description |
Isoleucine 2-epimerase |
Notes |
Sequences most similar to those of broad-specificity amino acid racemases (grouped in family 2.6.1.10) and to those of bacterial GABA transaminases (family 2.6.1.19b). |
PDB |
4YSN; |
PLP Fold Type |
I |
PLP-dependent Domain |
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Number of sequences |
9 |
Sequences in seed alignment |
|
Reference sequence |
AGE45209 |
Domain interval |
30-373 |
Catalytic site |
280 K |
| |
References |
Awad R, Gans P, Reiser JB (2017) Structural insights into the substrate recognition and reaction specificity of the PLP-dependent fold-type I isoleucine 2-epimerase from Lactobacillus buchneri Biochimie 137 165-173. Hayashi J, Mutaguchi Y, Minemura Y, Nakagawa N, Yoneda K, Ohmori T, Ohshima T, Sakuraba H (2017) Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri Acta Crystallogr D Struct Biol 73 428-437. Mutaguchi Y, Ohmori T, Wakamatsu T, Doi K, Ohshima T. (2013) Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species. J Bacteriol. 195 5207-15. Articles on 5.1.1.21 |
last changed |
2019/09/18 10:43 |
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