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B6db families: 5.1.1.5.c

5.1.1.5 c
Activity 5.1.1.5
Description Lysine racemase (family c)
Notes Very small family, based on the functionally validated enzyme from Thermotoga maritima. Sequences are quite dissimilar from those in familes 5.1.1.5_a and 5.1.1.5_b, but very similar to ornithine racemases (family 5.1.1.12). Indeed, the enzyme from Thermotoga also shows a very high activity towards L- and D-ornithine.
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Reference sequence NP_229397
Domain interval 8-226
Catalytic site 36 K
 
References
 Miyamoto T, Katane M, Saitoh Y, Sekine M, Homma H (2019) Elucidation of the D-lysine biosynthetic pathway in the hyperthermophile Thermotoga maritima FEBS J 286 601-614.

Articles on 5.1.1.5.c
last changed 2018/12/18 10:14

B6db families