B6db families : 2_1_2

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2.1.2.1

Activity

2.1.2.1

Description

Glycine hydroxymethyltransferase

Notes

Very distinct family of PLP enzymes, diffused in the three kingdoms of life.
In eukarya, the mitochondrial isozymes are more similar to the cytosolic isozymes than they are to hydroxymethyltransferases from bacteria and archaea.

PDB

1BJ4;1DFO;1EJI;1EQB;1KKJ;1KKP;1KL2;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Reference sequence

GLYA_ECOLI

Domain interval

8-386

Catalytic site

229 K

References

Articles on 2.1.2.1

last changed

2008/01/24 13:23