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B6db families:
Description Fluorothreonine transaldolase
Notes A similar family in the database is 2_1_2_7, D-alanine hydroxymethyltransferase. These enzymes include a -200aa C-terminal domain found also in other aldolases (not PLP-dependent) and possibly involved in binding a Zn(II) ion.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 5
Sequences in seed alignment
BacteriaWP_144383879 (Streptomyces sp. SAJ15); CAR92347 (Streptomyces cattleya); WP_042263688 (Nocardia brasiliensis); DH39445 (Streptomyces sp. MA37); SDK78082 (Actinopolyspora mzabensis);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence CAR92347
Domain interval 23-633
Catalytic site 248 K
 Wu L, Tong MH, Raab A, Fang Q, Wang S, Kyeremeh K, Yu Y, Deng H (2020) An unusual metal-bound 4-fluorothreonine transaldolase from Streptomyces sp. MA37 catalyses promiscuous transaldol reactions Appl Microbiol Biotechnol in press.

 Deng H, Cross SM, McGlinchey RP, Hamilton JT, O'Hagan D. (2008) In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase Chem Biol 15 1268-76.

Articles on
last changed 2020/03/07 15:33

B6db families