B6db families : 2_6_1_19

	Activities \| Families \| Sequences \| Fold types \| References \| Help

2.6.1.19 b

Activity

2.6.1.19

Description

4-aminobutyrate aminotransferase. (family b)

Notes

The gene from Pseudomonas putida has been tentatively assigned to delta-aminovalerate aminotransferase (2.6.1.48); however, the same gene has been included in this family based on its strict similarity to functionally validated GABA transaminases and (ii) on the known ability of GABA transaminases to use 5-aminovalerate as a substrate.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

CAE14640 (Photorhabdus luminescens); ZP_00024114 (Ralstonia metallidurans); AAQ61587 (Chromobacterium violaceum ); GABT_ECOLI (Escherichia coli); ZP_00095173 (Novosphingobium aromaticivorans); ZP_00017910 (Chloroflexus aurantiacus); GOAG_ECOLI (Escherichia coli); AAK21246 (Rhizobium leguminosarum); ZP_00086389.1 (Pseudomonas fluorescens ); ZP_00011871 (Rhodopseudomonas palustris); GABT_MYCTU (Mycobacterium tuberculosis); AF299291_2 (Pseudomonas putida); G83773 (Bacillus halodurans); GABT_BACSU (Bacillus subtilis); NP_629805 (Streptomyces coelicolor); H97075 (Clostridium acetobutylicum); ZP_00092384 (Azotobacter vinelandii); AAP24358 (Bacillus anthracis); NP_823759 (Streptomyces avermitilis ); ZP_00059063 (Thermobifida fusca);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

GABT_ECOLI

Domain interval

26-361

Catalytic site

268 K

References

Belitsky, B.R.; Sonenshein, A.L. (2002) GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis Mol Microbiol 45 569-83..

Schulz, A.; Taggeselle, P.; Tripier, D.; Bartsch, K. (1990) Stereospecific production of the herbicide phosphinothricin (glufosinate) by transamination: isolation and characterization of a phosphinothricin-specific transaminase from Escherichia coli Environ Microbiol 56 1-6.

Articles on 2.6.1.19.b

last changed

2007/11/26 18:27