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|
2.6.1.19 b |
Activity |
2.6.1.19 |
Description |
4-aminobutyrate aminotransferase (family b) |
Notes |
Family composed of bacterial enzymes, distantly related to those in subfamily 'a'. The sequences are most similar to the sequences in family 2.6.1.39_c. |
PDB |
1SFF;4ATQ; |
PLP Fold Type |
I |
PLP-dependent Domain |
|
Number of sequences |
23 |
Sequences in seed alignment |
|
Reference sequence |
GABT_ECOLI |
Domain interval |
26-361 |
Catalytic site |
268 K |
| |
References |
Hong J, Kim KJ (2019) Crystal structure of γ-aminobutyrate aminotransferase in complex with a PLP-GABA adduct from Corynebacterium glutamicum Biochem Biophys Res Commun 514 601-606. Wilding M, Walsh EF, Dorrian SJ, Scott C (2015) Identification of novel transaminases from a 12-aminododecanoic acid-metabolizing Pseudomonas strain Microb Biotechnol 8 665-72. Liu W, Peterson PE, Carter RJ, Zhou X, Langston JA, Fisher AJ, Toney MD.
(2004) Crystal structures of unbound and aminooxyacetate-bound Escherichia coli gamma-aminobutyrate aminotransferase Biochemistry 43 10896-905. Belitsky, B.R.; Sonenshein, A.L. (2002) GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis Mol Microbiol 45 569-83. Schulz, A.; Taggeselle, P.; Tripier, D.; Bartsch, K.
(1990) Stereospecific production of the herbicide phosphinothricin (glufosinate) by transamination: isolation and characterization of a phosphinothricin-specific transaminase from Escherichia coli
Appl Environ Microbiol 56 1-6. Articles on 2.6.1.19.b |
last changed |
2020/02/18 16:06 |
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