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|
2.6.1.2 c |
Activity |
2.6.1.2 |
Description |
Alanine aminotransferase (family c) |
Notes |
A group of enzymes based on the poorly characterized product of the E. coli gene yfdZ. The sequences are related to families involved in the transamination of diaminopimelate (2.6.1.83, 2.6.1.17) and of aromatic amino acids (e.g., 2.6.1.57b)
The enzyme from Aphanothece is indeed a promicuous catalyst acting also on diaminopimelate. |
PDB |
2X5D; |
PLP Fold Type |
I |
PLP-dependent Domain |
|
Number of sequences |
14 |
Sequences in seed alignment |
|
Reference sequence |
WP_016243747 |
Domain interval |
36-390 |
Catalytic site |
244 K |
| |
References |
Hasegawa D, Kito K, Maeda T, Rai V, Cha-Um S, Tanaka Y, Fukaya M, Takabe T (2019) Two groups of thermophilic amino acid aminotransferases
exhibiting broad substrate specificities for the synthesis
of phenylglycine derivatives Protoplasma 256 1727-1736. Yoneyama H, Hori H, Lim SJ, Murata T, Ando T, Isogai E, Katsumata R.
(2011) Isolation of a mutant auxotrophic for L-alanine and identification of three major aminotransferases that synthesize L-alanine in Escherichia coli Biosci Biotechnol Biochem 75 930-8. Articles on 2.6.1.2.c |
last changed |
2019/10/31 17:34 |
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