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B6db families: a
Description Alanine--glyoxylate aminotransferase (family a)
Notes The sequences included here are close homologs of alanine-glyoxylate aminotransferase 1 from rat liver organelles, which is identical to serine-glyoxylate aminotransferase ( and also to asparagine-oxo-acid aminotransferase ( [Noguchi & Fujiwara (1988) JBC 263, 182].

The enzymes from Drosophila and Aedes also show alanine-glyoxylate aminotransferase activity.

We have included in this family a number of bacterial sequences, as they seem very closely related to the metazoan ones. It must be remarked, however, that for none of these bacterial enzymes activity has been tested biochemically. Even for the Nostoc (Anabaena) enzyme, whose structure has been published, functional validation is lacking.

PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 0
Reference sequence SPYA_RAT
Domain interval 45-398
Catalytic site 231 K
References Articles on
last changed 2019/08/12 09:21

B6db families