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2.6.1.9
Activity 2.6.1.9
Description Histidinol-phosphate aminotransferase.
PDB 1FG7;1GEW;1IJI;1H1C;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm		Fold type I
Number of sequences
30
Sequences in seed alignment
ArchaeaHIS8_HALVO (Halobacterium volcanii); HIS8_PYRFU (Pyrococcus furiosus);
BacteriaHI81_RHIME (Rhizobium meliloti); ZP_00038941 (Xylella fastidiosa); HIS8_LACLA (Lactococcus lactis (subsp. lactis)); HIS8_MYCTU (Mycobacterium tuberculosis); HIS8_HAEIN (Haemophilus influenzae); HIS8_ECOLI (Escherichia coli); HIS8_XANCP (Xanthomonas campestris); NP_785979 (Lactobacillus plantarum); NP_743128 (Pseudomonas putida KT2440); HIS8_ZYMMO (Zymomonas mobilis); NP_738612 (Corynebacterium efficiens); ZP_00105735 (Nostoc punctiforme); CAD84558 (Nitrosomonas europaea ); ZP_00014927 (Rhodospirillum rubrum); HIS8_YERPE (Yersinia pestis); HIS8_SYNY3 (Synechocystis sp. (strain PCC 6803)); HIS8_THEMA (Thermotoga maritima); AAQ58289 (Chromobacterium violaceum ATCC 12472); HIS8_STRCO (Streptomyces coelicolor); NP_885050 (Bordetella parapertussis); HIS8_SALTY (Salmonella typhimurium); HI81_PASMU (Pasteurella multocida);
FungiHIS8_CANMA (Candida maltosa); XP_326215 (Neurospora crassa); HIS8_YEAST (Saccharomyces cerevisiae);
ViridiplantaeAAL87150 (Oryza sativa ); AAM51330 (Arabidopsis thaliana); CAA70403 (Nicotiana tabacum);

DISPLAY: Fasta format, alignment, hmm, hmm_local
Reference sequence HIS8_THEMA
Domain interval 19-331
Catalytic site 202 K
 
References
 Fernandez FJ, Vega MC, Lehmann F, Sandmeier E, Gehring H, Christen P, Wilmanns M. (2004) Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. J Biol Chem 279 21478-88.

 Mizuguchi H, Hayashi H, Miyahara I, Hirotsu K, Kagamiyama H. (2003) Characterization of histidinol phosphate aminotransferase from Escherichia coli Biochim Biophys Acta. 1647 321-4.

 El Malki, F.; Frankard, V.; Jacobs, M. (1998) Molecular cloning and expression of a cDNA sequence encoding histidinol phosphate aminotransferase from Nicotiana tabacum Plant Mol Biol 37 1013-22..

 Gu, W.; Zhao, G.; Eddy, C.; Jensen, R. A. (1995) Imidazole acetol phosphate aminotransferase in Zymomonas mobilis: molecular genetic, biochemical, and evolutionary analyses J Bacteriol 177 1576-84..

 Hsu, L. C.; Okamoto, M.; Snell, E. E. (1989) L-Histidinol phosphate aminotransferase from Salmonella typhimurium. Kinetic behavior and sequence at the pyridoxal-P binding site Biochimie 71 477-89..

Articles on 2.6.1.9
last changed 2007/09/08 13:19

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