B6db families : 2_6_1

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2.6.1.92

Activity

2.6.1.92

Description

UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase

Notes

Bacterial enzymes. The sequences are phylogenetically related to a number of other NDP-hexose aminotransferases.

PDB

2FN6;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_011138966 (Wolinella succinogenes); AAD06590 (Helicobacter pylori J99); WP_013325947 (Sulfurimonas autotrophica); WP_024955470 (Sulfurospirillum arcachonense); EAL53541 (Campylobacter upsaliensis); EAL57247 (Campylobacter coli); EAL54619 (Campylobacter lari); WP_000657244 (Helicobacter Pylori); WP_027327408 (Helicobacter pametensis); WP_013459015 (Sulfuricurvum kujiense); AAT12282 (Campylobacter jejuni); YP_664340 (Helicobacter acinonychis);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAT12282

Domain interval

7-364

Catalytic site

181 K

References

Schoenhofen IC, Lunin VV, Julien JP, Li Y, Ajamian E, Matte A, Cygler M, Brisson JR, Aubry A, Logan SM, Bhatia S, Wakarchuk WW, Young NM. (2006) Structural and functional characterization of PseC, an aminotransferase involved in the biosynthesis of Pseudaminic acid, an essential flagellar modification in helicobacter pylori. J Biol Chem. 281 8907-16.

Schoenhofen IC, McNally DJ, Vinogradov E, Whitfield D, Young NM, Dick S, Wakarchuk WW, Brisson JR, Logan SM. (2006) Functional characterization of dehydratase/aminotransferase pairs from Helicobacter and Campylobacter: enzymes distinguishing the pseudaminic acid and bacillosamine biosynthetic pathways J Biol Chem 281 723-32.

Obhi, R.K.; Creuzenet, C. (2005) Biochemical characterization of the Campylobacter jejuni Cj1294, a novel UDP-4-keto-6-deoxy-GlcNAc aminotransferase that generates UDP-4-amino-4,6-dideoxy-GalNAc J Biol Chem 280 20902-8.

Articles on 2.6.1.92

last changed

2018/07/16 14:58