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B6db families:
Description 4-aminobutyrate—pyruvate transaminase
Notes The sequences are similar to (beta-alanine--pyruvate aminotransferase) and indeed this enzyme, too, is an omega-amino acid--pyruvate aminotransferase.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
Sequences in seed alignment
ViridiplantaeAFS28621 (Malus domestica); AAC78480 (Capsicum chinense); AAO92255 (Lycopersicon esculentum); AAK11219 (Oryza sativa); AAO92256 (Lycopersicon esculentum); AGX01485 (Nicotiana tabacum); AAQ14479 (Oryza sativa); AAO92257 (Lycopersicon esculentum); AAK52899 (Arabidopsis thaliana);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence AAK52899
Domain interval 72-428
Catalytic site 327 K
 Nora Weber, Marie Gorwa-Grauslund and Magnus Carlquist (2014) Exploiting cell metabolism for biocatalytic whole-cell transamination by recombinant Saccharomyces cerevisiae Applied microbial and cell physiology .

 Christopher P. Trobacher, Shawn M. Clark, Gale G. Bozzo, Robert T. Mullen, Jennifer R. DeEll, Barry J. Shelp (2012) Catabolism of GABA in apple fruit: Subcellular localization and biochemical characterization of two gamma-aminobutyrate transaminases. Postharvest Biology and Technology 75 106-113.

 Clark SM, Di Leo R, Dhanoa PK, Van Cauwenberghe OR, Mullen RT, Shelp BJ. (2009) Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate J Exp Bot 60 1743-57.

 Van Cauwenberghe, O.R.; Makhmoudova, A.; McLean, M.D.; Clark, S.M.; Shelp, B.J. (2002) Plant pyruvate-dependent gamma-aminobutyrate transaminase:Identification of an Arabidopsis cDNA and its expression in Escherichia coli Can J Bot 80 933-41.

Articles on
last changed 2014/02/14 11:34

B6db families