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B6db families:
Description 4-aminobutyrate—pyruvate transaminase
Notes The sequences are similar to (beta-alanine--pyruvate aminotransferase) and indeed this enzyme, too, is an omega-amino acid--pyruvate aminotransferase.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 9
Sequences in seed alignment
ViridiplantaeAAC78480 (Capsicum chinense); AAK11219 (Oryza sativa); AAO92256 (Lycopersicon esculentum); AFS28621 (Malus domestica); AAQ14479 (Oryza sativa); AGX01485 (Nicotiana tabacum); AAO92257 (Lycopersicon esculentum); AAO92255 (Lycopersicon esculentum); AAK52899 (Arabidopsis thaliana);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence AAK52899
Domain interval 72-428
Catalytic site 327 K
 Weber N, Gorwa-Grauslund M, Carlquist M. (2014) Exploiting cell metabolism for biocatalytic whole-cell transamination by recombinant Saccharomyces cerevisiae Appl Microbiol Biotechnol 98 4615-24.

 Trobacher CP, Clark SM, Bozzo GG, Mullen RT, DeEll JR, Shelp BJ (2012) Catabolism of GABA in apple fruit: Subcellular localization and biochemical characterization of two gamma-aminobutyrate transaminases. Postharvest Biol Technol 75 106-113.

 Clark SM, Di Leo R, Dhanoa PK, Van Cauwenberghe OR, Mullen RT, Shelp BJ. (2009) Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate J Exp Bot 60 1743-57.

 Palanivelu R, Brass L, Edlund AF, Preuss D. (2003) Pollen tube growth and guidance is regulated by POP2, an Arabidopsis gene that controls GABA levels Cell 114 47-59.

 Van Cauwenberghe, O.R.; Makhmoudova, A.; McLean, M.D.; Clark, S.M.; Shelp, B.J. (2002) Plant pyruvate-dependent gamma-aminobutyrate transaminase:Identification of an Arabidopsis cDNA and its expression in Escherichia coli Can J Bot 80 933-41.

Articles on
last changed 2014/02/14 11:34

B6db families