|
|
2.6.99.3 |
Activity |
2.6.99.3 |
Description |
O-ureido-L-serine synthase |
Notes |
Family based on the functionally validated sequence from S. lavendulae, related to standard cysteine synthases. |
PDB |
3X43; |
PLP Fold Type |
II |
PLP-dependent Domain |
|
Number of sequences |
14 |
Sequences in seed alignment |
|
Reference sequence |
D2Z027 |
Domain interval |
8-292 |
Catalytic site |
43 K |
| |
References |
Uda N, Matoba Y, Kumagai T, Oda K, Noda M, Sugiyama M. (2013) Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway Antimicrob Agents Chemother 57 2603-12. Kumagai T, Koyama Y, Oda K, Noda M, Matoba Y, Sugiyama M (2010) Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae Antimicrob Agents Chemother 54 1132-9. Articles on 2.6.99.3 |
last changed |
2018/01/11 17:40 |
|