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B6db families: c
Description Cysteine desulfurase (family c)
Notes Very divergent family of enzymes, apparently occurring only in a few bacteria. The sequences are very distantly relted to (but shorter than) those in family
The prototype, YcfC from Erwinia amylovora, has been implicated in the synthesis of 6-thioguanine.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 10
Sequences in seed alignment
BacteriaWP_082315611 (Vibrio coralliilyticus); WP_004156388 (Erwinia amylovora); WP_092551865 (Xenorhabdus koppenhoeferi); WP_069318073 (Xenorhabdus ominickii); WP_034946285 (Erwinia oleae); WP_046221533 (Photobacterium halotolerans); WP_104087697 (Cryobacterium sp. N19); WP_053922280 (Streptomyces chattanoogensis); SMY05101 (Brevibacterium sp.239c); WP_012442179 (Erwinia tasmaniensis);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence WP_004156388
Domain interval 18-288
Catalytic site 148 K
 Hertweck C (2018) Enzymatic Thioamide Formation in Bacterial Antimetabolite Pathway Angew Chem Int Ed Engl 57 11574-11578.

Articles on
last changed 2020/02/20 14:44

B6db families