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B6db families: 2.8.1.9

2.8.1.9
Activity 2.8.1.9
Description molybdenum cofactor sulfurtransferase
Notes Desulfurases included in this family are eukariotic multidomain enzymes involved in the sulfuration of molybdenum enzyzmes such as xanthine oxidase.
Additional_domain JC7680 1-500
Additional C-terminal Mosc domain
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
7
Sequences in seed alignment
MetazoaNP_060417 (Homo sapiens); BAC22952 (Bombyx mori); BAA98138 (Bos taurus); AAM48348 (Drosophila melanogaster); XP_394734 (Apis mellifera);
ViridiplantaeAAL71858 (Lycopersicon esculentum); NP_564001 (Arabidopsis thaliana);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence NP_564001
Domain interval 37-487
Catalytic site 271 K
 
References
 Bittner, F.; Oreb, M.; Mendel, R.R. (2001) ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana J Biol Chem 276 40381-4.

 Ichida, K.; Matsumura, T.; Sakuma, R.; Hosoya, T.; Nishino, T. (2001) Mutation of human molybdenum cofactor sulfurase gene is responsible for classical xanthinuria type II Biochem Biophys Res Commun 282 1194-200.

Articles on 2.8.1.9
last changed 2014/07/11 16:49

B6db families