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B6db families: 4.1.1.105.a

4.1.1.105 a
Activity 4.1.1.105
Description L-tryptophan decarboxylase (family a)
Notes Family of bacterial enzymes, related to metazoan aromatic amino acid decarboxylases.

PDB 4OBV;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 5
Sequences in seed alignment
BacteriaAFH88381 (Bacillus atrophaeus); WP_003023076 (Blautia hansenii); WP_004612385 (Tyzzerella nexilis); WP_000164815 (Bacillus anthracis); EDN78222 (Ruminococcus gnavus ATCC 29149);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence EDN78222
Domain interval 54-416
Catalytic site 306 K
 
References
 Williams BB, Van Benschoten AH, Cimermancic P, Donia MS, Zimmermann M, Taketani M, Ishihara A, Kashyap PC, Fraser JS, Fischbach MA (2014) Discovery and characterization of gut microbiota decarboxylases that can produce the neurotransmitter tryptamine Cell Host Microbe 16 495-503.

 Yuwen L, Zhang FL, Chen QH, Lin SJ, Zhao YL, Li ZY. (2013) The role of aromatic L-amino acid decarboxylase in bacillamide C biosynthesis by Bacillus atrophaeus C89. Sci Rep. 3 1753.

Articles on 4.1.1.105.a
last changed 2019/03/12 13:27

B6db families