B6db families : 4_1_1_17

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4.1.1.17 2

Activity

4.1.1.17

Description

Ornithine decarboxylase. (family 2)

Notes

This family includes only eubacterial proteins. These are large, multidomain enzymes, whose key domain shows a fold-type I structure.
The family is well-defined, but related to family 4.1.1.18 (lysine decarboxylase) and 4.1.1.19_2 (arginine decarboxylase).

PDB

1ORD;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

CAC89803 (Yersinia pestis); DCOS_ECOLI (Escherichia coli); NP_715954 (Shewanella oneidensis); NP_965822 (Lactobacillus johnsonii); DCOR_ECOLI (Escherichia coli); ZP_00028786 (Burkholderia fungorum); DCOR_HAEIN (Haemophilus influenzae); NP_233445 (Vibrio cholerae ); NP_435606 (Sinorhizobium meliloti); ZP_00123170 (Haemophilus somnus); DCOR_LACS3 (Lactobacillus sp.); CAE27492 (Rhodopseudomonas palustris); NP_936119 (Vibrio vulnificus); CAJ32471 (Morganella morganii); NP_245743 (Pasteurella multocida);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

DCOR_LACS3

Domain interval

109-569

Catalytic site

356 K

References

de las Rivas B, Marcobal A, Muñoz R. (2007) Gene organization of the ornithine decarboxylase-encoding region in Morganella morganii J Appl Microbiol 102 1551-60.

Momany, C.; Ernst, S.; Ghosh, R.; Chang, N. L.; Hackert, M. L. (1995) Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution J Mol Biol 252 643-55..

Boyle SM, Barroso L, Moore RC, Wright JM, Patel T. (1994) Primary structure of the speC gene encoding biosynthetic ornithine decarboxylase in Escherichia coli Gene 151 157-60.

Hackert, M. L.; Carroll, D. W.; Davidson, L.; Kim, S. O.; Momany, C.; Vaaler, G. L.; Zhang, L. (1994) Sequence of ornithine decarboxylase from Lactobacillus sp. strain 30a J Bacteriol 176 7391-4..

Articles on 4.1.1.17.2

last changed

2008/01/03 14:20