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B6db families: 2
Description Ornithine decarboxylase (family 2)
Notes This family includes only eubacterial proteins. These are large, multidomain enzymes, whose key domain shows a fold-type I structure.
The family is well-defined, but sequences are related to lysine decarboxylases (families and and arginine decarboxylases (family
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 15
Sequences in seed alignment
BacteriaZP_00028786 (Burkholderia fungorum); DCOR_LACS3 (Lactobacillus saerimneri 30a); CAE27492 (Rhodopseudomonas palustris); DCOR_ECOLI (Escherichia coli); DCOS_ECOLI (Escherichia coli); NP_435606 (Sinorhizobium meliloti); NP_233445 (Vibrio cholerae ); CAC89803 (Yersinia pestis); NP_715954 (Shewanella oneidensis); ZP_00123170 (Haemophilus somnus); DCOR_HAEIN (Haemophilus influenzae); NP_936119 (Vibrio vulnificus); NP_245743 (Pasteurella multocida); CAJ32471 (Morganella morganii); NP_965822 (Lactobacillus johnsonii);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence DCOR_LACS3
Domain interval 109-569
Catalytic site 356 K
 Romano A, Trip H, Lolkema JS, Lucas PM (2013) Three-component lysine/ornithine decarboxylation system in Lactobacillus saerimneri 30a J Bacteriol 195 1249-54.

 de las Rivas B, Marcobal A, Muņoz R. (2007) Gene organization of the ornithine decarboxylase-encoding region in Morganella morganii J Appl Microbiol 102 1551-60.

 Momany, C.; Ernst, S.; Ghosh, R.; Chang, N. L.; Hackert, M. L. (1995) Crystallographic structure of a PLP-dependent ornithine decarboxylase from Lactobacillus 30a to 3.0 A resolution J Mol Biol 252 643-55.

 Boyle SM, Barroso L, Moore RC, Wright JM, Patel T. (1994) Primary structure of the speC gene encoding biosynthetic ornithine decarboxylase in Escherichia coli Gene 151 157-60.

 Hackert, M. L.; Carroll, D. W.; Davidson, L.; Kim, S. O.; Momany, C.; Vaaler, G. L.; Zhang, L. (1994) Sequence of ornithine decarboxylase from Lactobacillus sp. strain 30a J Bacteriol 176 7391-4.

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last changed 2019/12/12 18:46

B6db families