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B6db families: 1
Description Arginine decarboxylase (family 1)
Notes This family includes plant and proteobacterial (biosynthetic) arginine decarboxylases, which are fold-type III enzymes.
In contrast, the Escherichia coli biodegradative arginine decarboxylase and other bacterial arginine decarboxylases are fold-type I enzymes and have been grouped in family
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Number of sequences 29
Sequences in seed alignment
ViridiplantaeAEQ02349 (Erythroxylum coca);
BacteriaSPA1_SYNY3 (Synechocystis sp. (strain PCC 6803)); AAF09826 (Deinococcus radiodurans); CAE08874 (Synechococcus sp. WH 8102); AAD07486 (Helicobacter pylori 26695); BAC92011 (Gloeobacter violaceus); BAC09359 (Thermosynechococcus elongatus); NP_487441 (Nostoc sp. PCC 7120); SPEA_ECOLI (Escherichia coli); AAS81619 (Thermus thermophilus); Q9PPF5 (Campylobacter jejuni); YP_009641 (Desulfovibrio vulgaris); NP_233201 (Vibrio cholerae); NP_284719 (Neisseria meningitidis); ZP_00066511 (Microbulbifer degradans); NP_812306 (Bacteroides thetaiotaomicron); AAM38760 (Xanthomonas axonopodis); AAQ60544 (Chromobacterium violaceum);
ViridiplantaeCAE02767 (Oryza sativa); CDM81060 (Triticum aestivum); SPE1_ARATH (Arabidopsis thaliana); SPE1_PEA (Pisum sativum); SPE1_SOYBN (Glycine max); SPE1_DIACA (Dianthus caryophyllus); AAR08422 (Pringlea antiscorbutica); SPE2_ARATH (Arabidopsis thaliana); SPE1_BRAJU (Brassica juncea); SPE1_AVESA (Avena sativa); SPE1_ORYSA (Oryza sativa);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence SPE1_ARATH
Domain interval 107-384
Catalytic site 136 K
 Alam M, Srivastava A, Dutta A, Sau AK (2018) Biochemical and biophysical studies of Helicobacter pylori arginine decarboxylase, an enzyme important for acid adaptation in host IUBMB Life 70 658-669.

 Docimo T, Reichelt M, Schneider B, Kai M, Kunert G, Gershenzon J, D'Auria JC. (2012) The first step in the biosynthesis of cocaine in Erythroxylum coca: the characterization of arginine and ornithine decarboxylases. Plant Mol Biol. 78 599-615.

 Forouhar F1, Lew S, Seetharaman J, Xiao R, Acton TB, Montelione GT, Tong L. (2010) Structures of bacterial biosynthetic arginine decarboxylases. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66 1562-6.

 Hanfrey, C.; Sommer, S.; Mayer, M.J., Burtin, D., Michael, A.J. (2001) Arabidopsis polyamine biosynthesis: absence of ornithine decarboxylase and the mechanism of arginine decarboxylase activity Plant J 27 551-60.

 Sekowska, A.; Bertin, P.; Danchin, A. (1998) Characterization of polyamine synthesis pathway in Bacillus subtilis 168 Mol Microbiol 29 851-8.

 Bell, E.; Malmberg, R.L. (1990) Analysis of a cDNA encoding arginine decarboxylase from oat reveals similarity to the Escherichia coli arginine decarboxylase and evidence of protein processing Mol Gen Genet 224 431-6.

 Moore, R. C.; Boyle, S. M. (1990) Nucleotide sequence and analysis of the speA gene encoding biosynthetic arginine decarboxylase in Escherichia coli J Bacteriol 172 4631-40.

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last changed 2018/05/23 15:11

B6db families