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B6db families: b
Description Tyrosine decarboxylase (family b)
Notes This family includes solely archaeal enzymes, only distantly related to those in family a. The sequences in this family are most similar to archaeal aspartate-glutamate 1-decarboxylases.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 12
Sequences in seed alignment
ArchaeaZP_00148199 (Methanococcoides burtonii); YP_001047756 (Methanoculleus marisnigri JR1); WP_012065951 (Methanococcus vannielii); YP_008916484 (Methanobacterium sp. MB1); WP_011973718 (Methanococcus aeolicus); WP_007043501 (Methanotorris formicicus); NP_987251 (Methanococcus maripaludis); WP_013099471 (Methanocaldococcus infernus); WP_015733169 (Methanocaldococcus vulcanius); MFNA_METTP (Methanosaeta thermophila PT); WP_013180716 (Methanococcus voltae); Q60358 (Methanocaldococcus jannaschii);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence Q60358
Domain interval 11-390
Catalytic site 245 K
 Chellam Gayathri S, Manoj N (2019) Structural insights into the mechanism of internal aldimine formation and catalytic loop dynamics in an archaeal Group II decarboxylase J Struct Biol 208 137-151.

 Kezmarsky, N.D; Xu, H.; Graham, D.E.; White, R.H. (2005) Identification and characterization of a l-tyrosine decarboxylase in Methanocaldococcus jannaschii Biochim Biophys Acta 1722 175-182.

Articles on
last changed 2020/02/13 13:33

B6db families