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B6db families:
Description 2,2-dialkylglycine decarboxylase (pyruvate)
Notes Compact family, composed solely of bacterial and fungal enzymes. The activity is not documented in other organisms.
PDB 1D7S;1D7V;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 12
Sequences in seed alignment
BacteriaNP_631581 (Streptomyces coelicolor); ZP_00030273 (Burkholderia fungorum); DGDA_BURCE (Burkholderia cepacia); NP_396235 (Agrobacterium tumefaciens); ZP_00064168 (Leuconostoc mesenteroides); AAL17943 (Mycobacterium smegmatis);
FungiXP_328329 (Neurospora crassa); EAA74692 (Gibberella zeae); NP_594998 (Schizosaccharomyces pombe); AAM18795 (Mycosphaerella graminicola); EAA52810 (Magnaporthe grisea); EAA61842 (Aspergillus nidulans);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence DGDA_BURCE
Domain interval 28-367
Catalytic site 272 K
 Adachi, K.; Nelson, G.H.; Peoples, K.A.; DeZwaan, T.M.; Skalchunes, A.R.; Heiniger, R.W.; Shuster, J.R.; Hamer, L.; Tanzer, M.M. (2003) Sequence analysis and functional characterization of the dialkylglycine decarboxylase gene DGD1 from Mycosphaerella graminicola Curr genet 43 358-63.

 Keller, J. W.; Baurick, K. B.; Rutt, G. C.; O'Malley, M. V.; Sonafrank, N. L.; Reynolds, R. A.; Ebbesson, L. O.; Vajdos, F. F. (1990) Pseudomonas cepacia 2,2-dialkylglycine decarboxylase. Sequence and expression in Escherichia coli of structural and repressor genes J Biol Chem 265 5531-9.

Articles on
last changed 2008/01/30 13:54

B6db families