Activities | Families | Sequences | Fold types | References | Help
B6db families: 4.1.3.38.a

4.1.3.38 a
Activity 4.1.3.38
Description 4-amino-4-deoxychorismate lyase (family a)
Notes A family composed solely of bacterial enzymes, and based on the validated sequences from E. coli and Streptomyces sp.
PDB 1ET0;
PLP Fold Type IV
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type IV

Reference sequence PABC_ECOLI
Domain interval 37-261
Catalytic site 140 K
 
References
 Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, Hung LW, Baker EN, Lott JS, James MN, Terwilliger TC, Eisenberg DS, Sacchettini JC, Goulding CW. (2011) The TB Structural Genomics Consortium: a decade of progress Tuberculosis (Edinb) 91 155-72.

 Schadt HS, Schadt S, Oldach F, Süssmuth RD (2009) 2-Amino-2-deoxyisochorismate is a key intermediate in Bacillus subtilis p-aminobenzoic acid biosynthesis. J Am Chem Soc 131 3481-3.

 Zhang Y, Bai L, Deng Z. (2009) Functional characterization of the first two actinomycete 4-amino-4-deoxychorismate lyase genes Microbiology 155 2450-9.

 Green, J. M.; Nichols, B. P. (1991) p-Aminobenzoate biosynthesis in Escherichia coli. Purification of aminodeoxychorismate lyase and cloning of pabC J Biol Chem 266 12971-5.

Articles on 4.1.3.38.a
last changed 2014/02/25 11:18

B6db families