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B6db families:
Description 3-hydroxy-D-aspartate aldolase
Notes Family of bacterial enzymes, based on the validated sequences from Paracoccus denitrificans.
Their sequences are very strictly related to those of the enzymes in family (D-threonine aldolase, low specificity), which catalyze a similar reaction.
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Number of sequences
Sequences in seed alignment
BacteriaWP_006311598 (Agrobacterium sp. ATCC 31749); WP_007205929 (Yoonia vestfoldensis); WP_065325299 (Epibacterium mobile); WP_007803856 (Salipiger bermudensis); WP_007427775 (Oceaniovalibus guishaninsula); WP_011750152 (Paracoccus denitrificans DSM413); WP_009812829 (Roseovarius nubinhibens); WP_008558431 (Leisingera daeponensis); WP_011241927 (Ruegeria pomeroyi); WP_041545644 (Chelativorans sp. BNC1); YP_614695 (Ruegeria sp. TM1040); YP_003694550 (Starkeya novella ); WP_011280659 (Psychrobacter arcticus); Q8GRC8 (Paracoccus denitrificans IFO 13301); WP_010395298 (Paracoccus sp. J56); YP_008973975 (Leisingera methylohalidivorans); WP_011455725 (Jannaschia sp. CCS1); WP_009464597 (Ahrensia sp. R2A130);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence Q8GRC8
Domain interval 34-270
Catalytic site 62 K
 Schada von Borzyskowski L, Severi F, Krüger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Cortina NS, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ (2019) Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle Nature 575 500-504.

 Liu, J. Q.; Dairi, T.; Itoh, N.; Kataoka, M.; Shimizu, S. (2003) A novel enzyme, D-3-hydroxyaspartate aldolase from Paracoccus denitrificans IFO 13301: purification, characterization, and gene cloning Appl Microbiol Biotechnol 62 53-60.

Articles on
last changed 2019/11/18 09:18

B6db families