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B6db families:
Description 3-hydroxy-D-aspartate aldolase
Notes Family of bacterial enzymes, based on the validated sequences from Paracoccus denitrificans.
Their sequences are very strictly related to those of the enzymes in family (D-threonine aldolase, low specificity), which catalyze a similar reaction.
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Number of sequences 18
Sequences in seed alignment
BacteriaWP_041545644 (Chelativorans sp. BNC1); WP_065325299 (Epibacterium mobile); WP_011241927 (Ruegeria pomeroyi); WP_007427775 (Oceaniovalibus guishaninsula); YP_008973975 (Leisingera methylohalidivorans); WP_006311598 (Agrobacterium sp. ATCC 31749); YP_003694550 (Starkeya novella ); WP_011455725 (Jannaschia sp. CCS1); WP_009464597 (Ahrensia sp. R2A130); WP_007803856 (Salipiger bermudensis); WP_009812829 (Roseovarius nubinhibens); YP_614695 (Ruegeria sp. TM1040); WP_010395298 (Paracoccus sp. J56); WP_011750152 (Paracoccus denitrificans DSM413); WP_007205929 (Yoonia vestfoldensis); WP_008558431 (Leisingera daeponensis); WP_011280659 (Psychrobacter arcticus); Q8GRC8 (Paracoccus denitrificans IFO 13301);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence Q8GRC8
Domain interval 34-270
Catalytic site 62 K
 Schada von Borzyskowski L, Severi F, Krüger K, Hermann L, Gilardet A, Sippel F, Pommerenke B, Claus P, Cortina NS, Glatter T, Zauner S, Zarzycki J, Fuchs BM, Bremer E, Maier UG, Amann RI, Erb TJ (2019) Marine Proteobacteria metabolize glycolate via the β-hydroxyaspartate cycle Nature 575 500-504.

 Liu, J. Q.; Dairi, T.; Itoh, N.; Kataoka, M.; Shimizu, S. (2003) A novel enzyme, D-3-hydroxyaspartate aldolase from Paracoccus denitrificans IFO 13301: purification, characterization, and gene cloning Appl Microbiol Biotechnol 62 53-60.

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last changed 2019/11/18 09:18

B6db families