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B6db families: b
Description D-serine ammonia-lyase (family b)
Notes A family of fold-type III proteins, built based on the functionally validated sequences from yeast and chicken.
These eukaryotic proteins are more closely related to those of family (D-threonine aldolase, low specificity) than to those of bacterial D-amino acid ammonia-lyases. All three families, however, share the requirement of a divalent metal ion (in addition to PLP) for function.
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Reference sequence NP_011319
Domain interval 8-325
Catalytic site 60 K
 Ito T, Hemmi H, Kataoka K, Mukai Y, Yoshimura T. (2008) A novel zinc-dependent D-serine dehydratase from Saccharomyces cerevisiae Biochem J 409 399-406.

 Tanaka H, Yamamoto A, Ishida T, Horiike K. (2008) D-Serine dehydratase from chicken kidney: a vertebral homologue of the cryptic enzyme from Burkholderia cepacia J Biochem 143 49-57.

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last changed 2017/06/14 13:06

B6db families