B6db families : 4_4_1_35

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4.4.1.35 b

Activity

4.4.1.35

Description

L-cystine β-lyase (family b)

Notes

A small family of enzymes from Brassicaceae. The sequences are surprisingly close to those of validated nicotianamine aminotransferases (2.6.1.80) and to those of other aminotransferases. The family is apparently unrelated to family a (cyanobacterial C-DES enzymes).

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Viridiplantae

DY823946 (Taraxacum brevicorniculatum); ACC91267 (Capsella rubella); NP_194090 (Arabidopsis thaliana); AAO27362 (Brassica oleracea); AAK82963 (Arabidopsis thaliana);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAK82963

Domain interval

47-401

Catalytic site

245 K

References

Munt O, Prüfer D, Schulze Gronover C. (2013) A novel C-S lyase from the latex-producing plant Taraxacum brevicorniculatum displays alanine aminotransferase and l-cystine lyase activity. J Plant Physiol. 170 33-40.

Jones, P.R.; Manabe, T.; Awazuhara, M.; Saito, K. (2003) A new member of plant CS-lyases. A cystine lyase from Arabidopsis thaliana J Biol Chem 278 10291-6.

Articles on 4.4.1.35.b

last changed

2018/03/22 11:32