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B6db families: 4.4.1.9.b

4.4.1.9 b
Activity 4.4.1.9
Description L-3-cyanoalanine synthase (family b)
Notes Family composed of enzymes from insects, only distantly related to 4.4.1.9_a and most similar to cysteine synthase (E.C. 2.5.1.47).
PLP Fold Type II
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type II

Number of sequences 12
Sequences in seed alignment
MetazoaODM97401 (Orchesella cincta); XP_013172478 (Papilio xuthus); XP_021181539 (Helicoverpa armigera); AHY81319 (Tetranychus evansi); KOB72436 (Operophtera brumata); XP_011554718 (Plutella xylostella); XP_013190568 (Amyelois transitella); ALV66641 (Pieris rapae); EHJ66756 (Danaus plexippus); XP_017488846 (Rhagoletis zephyria); AHY81321 (Tetranychus urticae); XP_004932948 (Bombyx mori);

DISPLAY: Fasta format, alignment, hmm, hmm_local


Reference sequence AHY81321
Domain interval 16-313
Catalytic site 41 K
 
References
 Herfurth AM, van Ohlen M, Wittstock U (2017) β-Cyanoalanine Synthases and Their Possible Role in Pierid Host Plant Adaptation Insects 8 E62.

 van Ohlen M, Herfurth AM, Kerbstadt H, Wittstock U (2016) Cyanide detoxification in an insect herbivore: Molecular identification of β-cyanoalanine synthases from Pieris rapae Insect Biochem Mol Biol 70 99-110.

 Wybouw N, Dermauw W, Tirry L, Stevens C, Grbić M, Feyereisen R, Van Leeuwen T (2014) A gene horizontally transferred from bacteria protects arthropods from host plant cyanide poisoning Elife 3 e02365.

Articles on 4.4.1.9.b
last changed 2018/01/11 11:27

B6db families