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B6db families:
Description Isoleucine 2-epimerase
Notes Sequences most similar to those of broad-specificity amino acid racemases (grouped in family and to those of bacterial GABA transaminases (family
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 9
Sequences in seed alignment
BacteriaWP_009139250 (Slackia piriformis); YP_002633381 (Staphylococcus carnosus subsp. carnosus TM300); YP_007802199 (Gordonibacter pamelaeae 7-10-1-b); CCC57362 (Weissella thailandensis fsh4-2); YP_810017 (Oenococcus oeni PSU-1); WP_010021002 (Lactobacillus farciminis); WP_010008148 (Leuconostoc fallax); AGE45209 (Lactobacillus buchneri); WP_002488208 (Staphylococcus hominis);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence AGE45209
Domain interval 30-373
Catalytic site 280 K
 Awad R, Gans P, Reiser JB (2017) Structural insights into the substrate recognition and reaction specificity of the PLP-dependent fold-type I isoleucine 2-epimerase from Lactobacillus buchneri Biochimie 137 165-173.

 Hayashi J, Mutaguchi Y, Minemura Y, Nakagawa N, Yoneda K, Ohmori T, Ohshima T, Sakuraba H (2017) Crystal structure of the novel amino-acid racemase isoleucine 2-epimerase from Lactobacillus buchneri Acta Crystallogr D Struct Biol 73 428-437.

 Mutaguchi Y, Ohmori T, Wakamatsu T, Doi K, Ohshima T. (2013) Identification, purification, and characterization of a novel amino acid racemase, isoleucine 2-epimerase, from Lactobacillus species. J Bacteriol. 195 5207-15.

Articles on
last changed 2019/09/18 10:43

B6db families