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B6db families: b
Description Lysine racemase (family b)
Notes Very small family of enzymes based on the functionally validated sequence from Oenococcus oeni.
Thr224 and Trp355 have been described by Kato et al. as distinctive residues.
Sequences from other Leuconostocaceae, showing identity around 50% to the reference sequence and bearing the distinctive residues above have been included in the family. .
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Number of sequences 6
Sequences in seed alignment
BacteriaLYSR_OENOB (Oenococcus oeni); WP_075269335 (Weissella jogaejeotgali); WP_060391182 (Leuconostoc gelidum); P_014973616 (Leuconostoc carnosum); WP_007744745 (Oenococcus kitaharae); WP_002815692 (Leuconostoc mesenteroides);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence LYSR_OENOB
Domain interval 13-369
Catalytic site 39 K
 Palani K, Burley SK, Swaminathan S (2013) Structure of alanine racemase from Oenococcus oeni with bound pyridoxal 5'-phosphate Acta Crystallogr F Struct Biol Commun 69 15-9.

 Kato S, Hemmi H, Yoshimura T (2012) Lysine racemase from a lactic acid bacterium, Oenococcus oeni: structural basis of substrate specificity J Biochem 152 505-8.

Articles on
last changed 2018/02/12 16:20

B6db families