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B6db families: asp-glu.1.decarboxylase

asp-glu 1 decarboxylase
Activity asp-glu_1_decarboxylase
Description Aspartate/Glutamate 1-decarboxylase (4.1.1.-)
Notes Archaeal enzymes, very similar to archaeal tyrosine decarboxylase (family Indeed some of the enzymes in this family can decarboxylate tyrosine.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 13
Sequences in seed alignment
ArchaeaWP_048056048 (Pyrococcus sp. ST04); WP_004067296 (Thermococcus litoralis); YP_004623572 (Pyrococcus yayanosii); WP_048165689 (Palaeococcus pacificus); WP_058938500 (Thermococcus celericrescens); Q8U1P6 (Pyrococcus furiosus); BAD86003 (Thermococcus kodakaraensis); YP_004072136 (Thermococcus barophilus ); NP_126894 (Pyrococcus abyssi); O58679 (Pyrococcus horikoshii OT3); WP_068322192 (Pyrococcus kukulkanii); KUK18325 (Thermococcus sibiricus); YP_002308097 (Thermococcus onnurineus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence BAD86003
Domain interval 53-334
Catalytic site 231 K
 Tomita H, Yokooji Y, Ishibashi T, Imanaka T, Atomi H (2014) An archaeal glutamate decarboxylase homolog functions as an aspartate decarboxylase and is involved in β-alanine and CoA biosynthesis J Bacteriol 196 1222-30.

 Lee ES, Kim HW, Kim DE, Kim YH, Nam SW, Kim BW, Jeon SJ (2013) Gene expression and characterization of thermostable glutamate decarboxylase from Pyrococcus furiosus Biotechnol Bioproc Engin 18 375-381.

 Kim HW, Kashima Y, Ishikawa K, Yamano N (2009) Purification and characterization of the first archaeal glutamate decarboxylase from Pyrococcus horikoshii Biosci Biotechnol Biochem 73 224-7.

Articles on asp-glu.1.decarboxylase
last changed 2017/10/12 14:30

B6db families