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B6db families: cuab

Activity cuab
Description Curvulamine intermediate synthase (2.3.1.-)
Notes A small family of fungal enzymes.
Their reaction is somewhat similar to that of fum8 enzymes, but sequences are related only distantly. Instead, proteins in this family most closely resemble 8-amino-7-oxononanoate synthases (family
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 5
Sequences in seed alignment
FungiXP_014072737 (Bipolaris maydis ATCC 48331); XP_007711337 (Bipolaris zeicola 26-R-13); QHD56301 (Curvularia sp. IFB-Z10); XP_007700279 (Bipolaris sorokiniana ND90Pr); XP_007689407 (Bipolaris oryzae ATCC 44560);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence QHD56301
Domain interval 61-440
Catalytic site 277 K
 Dai GZ, Han WB, Mei YN, Xu K, Jiao RH, Ge HM, Tan RX (2020) Pyridoxal-5'-phosphate-dependent bifunctional enzyme catalyzed biosynthesis of indolizidine alkaloids in fungi Proc Natl Acad Sci U S A. 117 1174-1180.

Articles on cuab
last changed 2020/02/17 09:50

B6db families