B6db families : genb1

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genb1

Activity

genb1

Description

6'-deoxy-6'(S)-amino-geneticin aminotransferase (2.6.1.-)

Notes

The activity has just put in the data base as 2_6_1_93. It will be took off from the data base.

PDB

6CBO;5Z83;

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

AGB13915 (Micromonospora echinospora); ACN38339 (Micromonospora inyonensis); SCL39651 (Micromonospora pallida); 2585707721 (Micromonospora sagamiensis DSM 43912);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AGB13915

Domain interval

17-368

Catalytic site

232 K

References

Ban YH, Song MC, Hwang JY, Shin HL, Kim HJ, Hong SK, Lee NJ, Park JW, Cha SS, Liu HW, Yoon YJ (2019) Complete reconstitution of the diverse pathways of gentamicin B biosynthesis Nat Chem Biol 15 295-303.

Dow GT, Thoden JB, Holden HM (2018) The Three-Dimensional Structure of NeoB: An Aminotransferase Involved in the Biosynthesis of Neomycin Protein Sci 27 945-956.

Gu Y, Ni X, Ren J, Gao H, Wang D, Xia H. (2015) Biosynthesis of Epimers C2 and C2a in the Gentamicin C Complex. Chembiochem. 16 1933–1942.

Articles on genb1

last changed

2019/01/21 12:51