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B6db families: genb1

Activity genb1
Description 6'-deoxy-6'(S)-amino-geneticin aminotransferase (2.6.1.-)
Notes The activity has just put in the data base as 2_6_1_93. It will be took off from the data base.
PDB 6CBO;5Z83;
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 4
Sequences in seed alignment
BacteriaAGB13915 (Micromonospora echinospora); ACN38339 (Micromonospora inyonensis); SCL39651 (Micromonospora pallida); 2585707721 (Micromonospora sagamiensis DSM 43912);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence AGB13915
Domain interval 17-368
Catalytic site 232 K
 Ban YH, Song MC, Hwang JY, Shin HL, Kim HJ, Hong SK, Lee NJ, Park JW, Cha SS, Liu HW, Yoon YJ (2019) Complete reconstitution of the diverse pathways of gentamicin B biosynthesis Nat Chem Biol 15 295-303.

 Dow GT, Thoden JB, Holden HM (2018) The Three-Dimensional Structure of NeoB: An Aminotransferase Involved in the Biosynthesis of Neomycin Protein Sci 27 945-956.

 Gu Y, Ni X, Ren J, Gao H, Wang D, Xia H. (2015) Biosynthesis of Epimers C2 and C2a in the Gentamicin C Complex. Chembiochem. 16 19331942.

Articles on genb1
last changed 2019/01/21 12:51

B6db families