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B6db families: gm853

Activity gm853
Description Leucine decarboxylase (4.1.1.-)
Notes Family built around three functionally validated enzyme from mouse.
These are Fold-type III sequences, very closely related to those in family 4.1.17_1 (ornithine decarboxylases) and odcp (ornithine decarboxylase antizyme inhibitor).
PLP Fold Type III
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type III

Number of sequences 10
Sequences in seed alignment
MetazoaXP_002720724 (Oryctolagus cuniculus); XP_020018672 (Castor canadensis); XP_232777 (Rattus norvegicus); XP_019694617 (Felis catus); XP_006158213 (Tupaia chinensis); XP_008693048 (Ursus maritimus); ERE85399 (Cricetulus griseus); XP_006503261 (Mus musculus); XP_020951430 (Sus scrofa); XP_019585704 (Rhinolophus sinicus);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence XP_006503261
Domain interval 52-385
Catalytic site 81 K
 Lambertos A, Ramos-Molina B, Cerezo D, López-Contreras AJ, Peñafiel R (2018) The mouse Gm853 gene encodes a novel enzyme: Leucine decarboxylase Biochim Biophys Acta 1862 365-376.

Articles on gm853
last changed 2019/02/13 13:28

B6db families