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B6db families: hpgt.aminotransferase

hpgt aminotransferase
Activity hpgt_aminotransferase
Description L-4-hydroxyphenylglycine aminotransferase (2.6.1.-).
Notes The family includes the bacterial sequences most similar to the validated gene products from Streptomyces lavendulae and Amycolatopsis orientalis.
More distantly related sequences also occur in Nocardia (NocG, in the gene cluster for the biosynthesis of Nocardicin A) and other bacteria, but they have not been included here.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences
Sequences in seed alignment
BacteriaCAC48367 (Amycolatopsis balhimycina); CAD91232 (Nonomuraea sp. ATCC 39727); CAA11790 (Amycolatopsis orientalis); AAK81836 (Streptomyces lavendulae);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence CAA11790
Domain interval 65-425
Catalytic site 266 K
 Chiu, H. T.; Hubbard, B. K.; Shah, A. N.; Eide, J.; Fredenburg, R. A.; Walsh, C. T.; Khosla, C. (2001) Molecular cloning and sequence analysis of the complestatin biosynthetic gene cluster Proc Natl Acad Sci U S A 98 8548-53.

 Hubbard BK, Thomas MG, Walsh CT. (2000) Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics Chem Biol 7 931-42.

Articles on hpgt.aminotransferase
last changed 2007/12/12 15:40

B6db families