B6db families : lnmj-sh

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lnmj-sh

Activity

Description

Polyketide synthase cysteine conjugate lyase domain (4.3.1.-)

Notes

The validated PLP-dependent domain, upon which the family is based, was extrapolated from the complete polyketide synthase sequence of Streptomyces atroolivaceus.
Sequences in this family are most closely related to those in family 4.1.99.2, Tyrosine phenol-lyase.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_059300321 (Streptomyces canus); AAN85523 (Streptomyces atroolivaceus); KJK59202 (Saccharothrix sp. ST-888); SDD61903 (Alloactinosynnema iranicum); SCE73393 (Micromonospora tulbaghiae); WP_047122366 (Streptomyces leeuwenhoekii);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

AAN85523

Domain interval

40-364

Catalytic site

248 K

References

Ma M, Lohman JR, Liu T, Shen B. (2015) C-S bond cleavage by a polyketide synthase domain. Proc Natl Acad Sci U S A. 122 10359-64.

Articles on lnmj-sh

last changed

2019/02/13 13:32