B6db families : pgat

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pgat

Activity

Description

Phenylglycine aminotransferase (2.6.1.-)

Notes

The family includes the bacterial sequences most similar to the characterized enzyme from Streptomyces pristinaespiralis.
The closest family in the database is 2.6.1.103 (L-4-hydroxyphenylglycine aminotransferase), whose reaction is very similar to that of pgat.

PLP Fold Type

PLP-dependent Domain

Domain alignment
Domain hmm

Fold type I

Number of sequences

Sequences in seed alignment

Bacteria

WP_078505150 (Streptomyces sp. TAA204); CBH31050 (Streptomyces pristinaespiralis); WP_100598466 (Streptomyces sp. CB01635); WP_089156235 (Micromonospora sp. NBS 11-29); WP_033226916 (Streptomyces virginiae); WP_011028839 (Streptomyces coelicolor); WP_093769430 (Streptomyces sp. F-7);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence

CBH31050

Domain interval

56-427

Catalytic site

268 K

References

Osipenkov N, Kulik A, Mast YJ (2018) Characterization of the phenylglycine aminotransferase PglE from Streptomyces pristinaespiralis J Biotechnol 278 34-38.

Liu SP, Liu RX, El-Rotail AA, Ding ZY, Gu ZH, Zhang L, Shi GY (2014) Heterologous pathway for the production of L-phenylglycine from glucose by E. coli J Biotechnol 186 91-7.

Mast YJ, Wohlleben W, Schinko E. (2011) Identification and functional characterization of phenylglycine biosynthetic genes involved in pristinamycin biosynthesis in Streptomyces pristinaespiralis J Biotechnol 155 63-7.

Articles on pgat

last changed

2019/05/17 10:04