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B6db families: plu3042

Activity plu3042
Description 3,4-dihydrotyrosine transaminase (2.6.1.-)
Notes Proteins very similar to those in family tuzn1299 (archaeal, low-specificity branched-chain amino acid transaminases).

In effect, some sequences such as WP_006137606 from Streptomyces griseoaurantiacus should belong to this family based on gene clustering, but sequence-wise show a slightly higher identity with validated enzymes in the tuzn1299 family.

PLP Fold Type IV
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type IV

Number of sequences 10
Sequences in seed alignment
BacteriaELP24967 (Pantoea agglomerans 299R); AHG21712 (Chania multitudinisentens RB-25); WP_050980294 (Halomonas stevensii S18214); WP_077337055 (Vibrio ruber); WP_038903922 (Dickeya zeae); EQB99558 (Photorhabdus temperata subsp. temperata M1021); WP_004158238 (Erwinia amylovora); WP_012667755 (Erwinia pyrifoliae); WP_005743267 (Pseudomonas syringae ICMP 19498); CAE15416 (Photorhabdus luminescens subsp. laumondii TTO1);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence CAE15416
Domain interval 41-276
Catalytic site 212 K
 Crawford JM, Mahlstedt SA, Malcolmson SJ, Clardy J, Walsh CT (2011) Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis Chem Biol 18 1102-12.

Articles on plu3042
last changed 2018/02/21 10:11

B6db families