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B6db families: rubn4

Activity rubn4
Description dTDP-3,4-didehydro-2,6-dideoxy-D-glucose aminotransferase (2.6.1.-)
Notes A small family of bacterial enzymes, strictly related to enzymes (such as and that also produce TTP-3-amino-deoxyhexoses.
PLP Fold Type I
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type I

Number of sequences 15
Sequences in seed alignment
BacteriaAAP85347 (Streptomyces griseoruber); ZP_04032501 (Thermomonospora curvata); ABV49595 (Streptomyces eurythermus); EEK34299 (Nocardiopsis dassonvillei); YP_001537186 (Salinispora arenicola); ACB37737 (Micromonospora chalcea); BAC79028 (Streptomyces sp. AM-7161); CAI94698 (Streptomyces achromogenes subsp. rubradiris); DNRJ_STRPE (Streptomyces peucetius); ACB46490 (Actinomadura kijaniata); AAG13910 (Micromonospora megalomicea); CAA11782 (Amycolatopsis orientalis); AVO00806 (Streptomyces sp. 120454); BAB72037 (Streptomyces galilaeus); CAC48376 (Amycolatopsis balhimycina);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence CAI94698
Domain interval 13-367
Catalytic site 186 K
 Lamichhane J, Liou K, Lee HC, Kim CG, Sohng JK. (2006) Functional characterization of ketoreductase (rubN6) and aminotransferase (rubN4) genes in the gene cluster of Streptomyces achromogenes var. rubradiris Biotechnol Lett 28 545-53.

 Chen H, Thomas MG, Hubbard BK, Losey HC, Walsh CT, Burkart MD. (2000) Deoxysugars in glycopeptide antibiotics: enzymatic synthesis of TDP-L-epivancosamine in chloroeremomycin biosynthesis Proc Natl Acad Sci U S A 97 11942-7.

Articles on rubn4
last changed 2014/08/19 13:41

B6db families