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B6db families: tuzn1299

Activity tuzn1299
Description Branched chain amino acid--pyruvate transaminase (low-specificity) (2.6.1.-)
Notes Family composed only of archaeal enzymes. The most similar sequences in the database are found in family (classic branched-chain amino acid aminotransferase).
PLP Fold Type IV
PLP-dependent Domain
Domain alignment
Domain hmm
Fold type IV

Number of sequences 10
Sequences in seed alignment
ArchaeaABO09173 (Pyrobaculum calidifontis JCM 11548); KUO83260 (Pyrobaculum sp. JCHS_4); WP_013680111 (Thermoproteus uzoniensis); WP_069807611 (Vulcanisaeta thermophila); WP_014126068 (Thermoproteus tenax); WP_013604112 (Vulcanisaeta moutnovskia); KJR73586 (Thermoproteus sp. AZ2); AAL64820 (Pyrobaculum aerophilum str. IM2); AET32742 (Pyrobaculum ferrireducens); WP_081226729 (Thermoproteus sp. CP80);

DISPLAY: Fasta format, alignment, hmm, hmm_local

Reference sequence WP_013680111
Domain interval 29-258
Catalytic site 150 K
 Stekhanova TN, Rakitin AL, Mardanov AV, Bezsudnova EY, Popov VO (2017) A Novel highly thermostable branched-chain amino acid aminotransferase from the crenarchaeon Vulcanisaeta moutnovskia Enzyme Microb Technol 96 127-134.

 Bezsudnova EY, Stekhanova TN, Suplatov DA, Mardanov AV (2016) Experimental and computational studies on the unusual substrate specificity of branched-chain amino acid aminotransferase from Thermoproteus uzoniensis Arch. Biochem. Biophys. 607 27-36.

 Boyko KM, Stekhanova TN, Nikolaeva AY, Mardanov AV, Rakitin AL, Ravin NV, Bezsudnova EY, Popov VO (2016) First structure of archaeal branched-chain amino acid aminotransferase from Thermoproteus uzoniensis specific for L-amino acids and R-amines Extremophiles 20 215-25.

Articles on tuzn1299
last changed 2017/12/22 08:27

B6db families