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amine transaminase |
Activity |
amine_transaminase |
Description |
Aromatic amine--pyruvate aminotransferase (2.6.1.-) |
Notes |
A family of bacterial enzymes built on the validated sequences from V. fluvialis and C. violaceum. The physiological function of these anzymes is not known, but they are potentially useful for biocatalytic methods of organic synthesis. The most closely related sequences belong to 2.6.1.113 (Putrescine--pyruvate aminotransferase). |
PLP Fold Type |
I |
PLP-dependent Domain |
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Number of sequences |
8 |
Sequences in seed alignment |
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Reference sequence |
AEA39183 |
Domain interval |
32-385 |
Catalytic site |
285 K |
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References |
Seo JH, Park HY, Kim J, Lee BS, Kim BG. (2008) Exploring sequence space: profile analysis and protein-ligand docking to screen omega-aminotransferases with expanded substrate specificity Biotechnol J 3 676-86. Kaulmann, U.; Smithies, K.; Smith, M.E.B.; Hailes, H.C.; Ward, J.M. (2007) Substrate spectrum of omega-transaminase from Chromobacterium violaceum DSM30191 and its potential for biocatalysis Enzyme Microb Tech 41 628-637. Shin JS, Yun H, Jang JW, Park I, Kim BG. (2003) Purification, characterization, and molecular cloning of a novel amine:pyruvate transaminase from Vibrio fluvialis JS17 Appl Microbiol Biotechnol 61 463-71. Articles on amine.transaminase |
last changed |
2017/09/08 09:16 |
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